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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548eccf0b34a64f65d9f2be556cf8e569b27ab5f085548fe9c00ca50a664bdf5' 
  AND token = '5GwM7gDKs7PpkDFuj5YJFBt1ogi24+sEbkV/DWRfduI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}