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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df946bd7c60e1a0f9f1d2c47e17870afa04e7b8350f7bc77b3d751987457a435' 
  AND token = 'dtZ6kKhCEMS7ClXDqhRYzUuogPJh3klcHsx5EX7eCJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}