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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309ecee5b994d531acc5623a00eef1944c70ad11a07d63d9287a7aecc8a6a34d' 
  AND token = 'M+vJrWCyl7kcdTgDVEpSErDwvYXGMUTW5T9765utp7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}