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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e782a63f691a7d820f75235ddc9d71dc8be0325099b4edf302fb60e866f68403' 
  AND token = 'GQFoxrN+ClKaUMM9S0fx/W38zO2Vrxnh6psDzzg1v1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}