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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a15a75efe2bf02086ef8afa5f78a4a4ffea97b32541b0ff287ac62148ae06980' 
  AND token = 'I7cnpxqi48Gp4Z0CooCp+lYmyGOp+XmRvGupuEIfMlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}