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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159cecb93223e3fa7ae8cc38073522eb05dbc85e0bd5e0d95e220066cae7287f' 
  AND token = 'cFtMK86YAY5cvO3B/0Q3sP7u9ho70BTC3U0he8yWxfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}