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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '312deeae5b9d9fcb044a25164e53fec5049a1b070d3c4f080eb6acea02b83b26' 
  AND token = '4Ng5bWh2gQCwwKTShnP58pJJZj8AUEn2uBL3X9M9sqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}