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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '98b54c4e88064e91149b4b1d18da231b5f365a4b9a9feb878de627c6205c8f8a' 
  AND token = 'FPD9CdAlbgRO/D6L9+0VZdW+roZfZqr0uES4+fdaOQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}