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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a26d5249940d90715c56ad1ef552371e47c8dce631fb6a3c18850856d7bbc7' 
  AND token = 'KaOU4Hu6TGwcaS84G2hTgMKYhN7IhJlxaE+lftDmOeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}