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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aedf06856758269fb260fc7a95e7870c2259b33483fddf67565e1aeb92ba8f7' 
  AND token = 'Y/r15aFybiHwn9nXS4g+EaKSEC+Wd0+qyTZ2tYIghn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}