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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dce86963f183e87d750f913945ec412b19a56e6df6b948bc8142c96949c2e87d' 
  AND token = 'PJo7cS2wK9HuIPKcMjKELrBmfTFn3W1+BGSeeyKSJ2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}