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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15909731f6b9c33e3f50a729b203a04360530e53e7d23633c3026cbf28650d60' 
  AND token = '8crMg/8bRSdxOg4LcUmCB/p4fudkzxyNlOBaFRWs0DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}