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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8318b4966489c28357103aff978cb04f2060cec5996ef8ad93f5cb1eeed7a2d0' 
  AND token = 'mIQC5HiQ38NsiH92Ng4YWj86O2NY0B2qqCYpwvK9C0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}