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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd511052232b2342e8567bc867839f9049e254d1cc04738c267077255f88ec3d0' 
  AND token = 'Dkm6AqEPynOWc11ACPgAICWRaBNRz4Kgmrk0pTDEnQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}