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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee14f123b1d2de2b5b6a9023d7b451d56fb4784f6c77dbb100311c0271b2407e' 
  AND token = 'OgitL/dbj1MGNuzlb5CQU0RHqLXYFwwOZKBwtYCjwtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}