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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d1bf98b5b20f177e69ea9c24084ab07b2ba445fe35487b5a94c5b6f94981dd2' 
  AND token = 'AGW/+0xVx4whQV7Fd+MN2GwzpWtJmxEa3+Axjt5mHrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}