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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd925d3d3d7d13ffc9331616f1d831bea8c5c1af97c56024fd4b36addeef1a217' 
  AND token = 'OfnaUKmOC4vYBB3KrycDg50R6UJdXoTbNlD+WSllCS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}