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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2321950040a464fd20630d7b8ac401aab42e1617ebaa3506b32f788f83a50b2' 
  AND token = '8gwoUAfDrB7Gq6LAkiZrx4cXN0SCc2yHvQZXW8cbOOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}