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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2afd0d67978db8c7911037ffef482bdb51bab68ee332fcd8e01ad9a2f25143' 
  AND token = 'HcacknAsi5gk6WZ7iBepcVtpd7OK/oUFerkOK1dps44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}