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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16d2130a1e9079590f5a5e1e35014b6b6ee29b302da7c334f82bf22c3121ad6' 
  AND token = 'hyKSZr0tPsQGLq7voRt6yOFomUSwKxYAsaDYOXmc2G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}