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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc51283c192e2bcd9c559c72e3e7c6f1aa54a623a47f06857f5a08f116f547f' 
  AND token = 'HnmrTh6UlYTUw/31nJ8G28xsIA5RoxOdSYpTiE6jsKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}