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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2373b9e74b6c4c05852cbc4998dba759027ee043b92a63ef08643ee196a04540' 
  AND token = 'uSopDU+M6M37nDJQeZiJnYFuJRjefe5N+uxxZP50Gzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}