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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265697e2e8fd52fbcbe17911134edccf02087d7e846c6c4e1efd3e868b0c0783' 
  AND token = 't6AJwdWRam/T2r4ssJ5tAk6cbMY0Y/LwyD3z+ieHR1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}