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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29f144dd76fd2f6a97cb792cf119e09c63bcc9b9391fd77ad0fb29943382d0d' 
  AND token = 'bXX8a5pRmgfPDJcsgfBFNwo0DuX+pd+lbux0SzKJV4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}