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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a8bb89f67452672f399df0e31f3969b6084d3083d6dcc0718bfbeba527faa5' 
  AND token = '10ohmTowDGmRLbqaddwOD+quLMfB4fcizUt171ATGFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}