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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a578aa49661bd5e53886fd4e9a4569730d74761c1b172e40ef864d9e0ef076' 
  AND token = 'kVhk7UXaxWDG2oUbbMPBt5QGIsVZRzn2jYmWb58nrls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}