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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10afa87494840366c7af3ab4482ba7306f705dca29d103256cb450f0c8a20c95' 
  AND token = 'nf5jG2VFxUJe6/T+R57pHgyHLSuGJQ1N4y7aUT15OX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}