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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7d5d72115b316839b802c8ce9b5a29be0e50b41aaca246b403cf62cd559507' 
  AND token = 't5WQLOHo5Q/NJhMinPgf5mzdVCfBZnW/VGsdMMedx0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}