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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '244f0c6c1cf9af712ca9ccd78b7b5337f4d15ee5e00cf062d1110d7c42406513' 
  AND token = 'oBuPliq7Gpz3U3hp7xTGOIlgIVPcSB5RnNN4aEZKswE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}