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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e60faa5187d3714f6b7af4d69a0ae7c0caa65192e1fb79db7956fde1de23be2' 
  AND token = 'utMUP1QHPUKDHlyKZgCkEAdFa/2iIUdX7BdqFMHKjWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}