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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235505ec27bf125fd3347b6fc8d7f134586eda8a2221a60981539ac2cdcf2d0e' 
  AND token = 'tM2vMo2AWaUhwheSGECWD41uzZiqKJiiMm/dNz0Hieg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}