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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499749c5b91572545a8d836218f334ca8e8c08c4349bcd8d64576aba2faefa11' 
  AND token = 'QPcuQ6n6ya+x03+Smkc2BAVF7dBjA22l/Ch5vCXEkCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}