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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4674d34ff59a03fbd1a2d7bcb7fb69c236c980eb60b68261132dd2ef259e132' 
  AND token = 'Bx+09r237ll/D9fjrcaxgeKzHO1BQ7zKpQMRqbX+Wr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}