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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c78b928301cdc844587f28473d08104490e5e501bc9f60f2d1444fdf003f0882' 
  AND token = '5FFhR1rOubio16LxoKzCuxfQ/9f5jjFemAJ5gtWYYO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}