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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b6b9f5e79b48503604c257f8170d763d8e13129aa67d02b351e465f8e7bad03' 
  AND token = '7lHY0tlW/JxaDtgKwEIo3o0XnNeOyUIGAGTW+V+OPCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}