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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53718b6440c754e92e4517c22a0f9f1064d56087bd00892b60bd14651ec3b46' 
  AND token = 'Nsd4cu0Gx/ZBuZ2YAWi9qclUrrdFTxvftn2K+u+7rQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}