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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203ed5b3cfd53fd7a5f741b9e5cd067f7c184b3dd187d53d86fe850fecceeb48' 
  AND token = 'MV8HwkVNtygVnNT+dx7rVpyU+hVfNKDc6mI5U4YjmD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}