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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c168b238998fa8f583f2272856efc66cfc9873e9b649ffac4f69eab9666ba86' 
  AND token = 'aKIyz1feb8SjJ7YRuiIYRP5KK0NdsR6/YJN4JcBJN6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}