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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f7308a5331f8e4e7b27344de013e02c848cb0c5394b1acf499b932de628a44' 
  AND token = 'DMYI6r2WIe9tmFw9RoXHvyWTyOFmY8GHcoJKtQV8O4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}