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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d2b0772db70aaab3e4b328a7960ab9e703519ef4d6c01d460dcdd158d58e41' 
  AND token = '2OuxwkTc4E9FW2Pqrg9SkyZFrjpVYyatel2cRH1XLGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}