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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '94e0e715305584a8526b1dd87e5093c4381304975fd2b795f58e405a73c22eda' 
  AND token = 'Ya/EXsUjxGOisj3AL6oS7ejs5TNw4fKoIk9Aqsmu+nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}