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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5811b8b8009ab8789b8dfe58df8e015b67687c1844a1d56a52f2dc1127dc1c09' 
  AND token = 'QjsNWtLWlYxmo8Ogfo8hr6yMxxfHwhuRZ4kRBU7scL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}