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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353641ef5e1e49b7a3a79043a6c674e4bdd5d232cb123a1748d5311ee7e63087' 
  AND token = '6AtCMjT+0HyGfbZohbIqlA2eT6yqBmgH2DH5A8+fy1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}