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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd195e6bcd3c15eb2f72b69ec1879e5a1faff87d5990426490a5feb4ecbeebe0c' 
  AND token = 'TqPQEGVLb3pOVyksgFjGF6UdyaVBi+eYmv68mDoAtaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}