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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de896296c128b4926ce3a301306d651c2101f3e30f44f06bff6c22eb895a45b7' 
  AND token = 'US3ihlIvva4c5mznVH+0/zpV6NHvNS0o+bkcLr6CRlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}