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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57d5e61c683be495ad418965c0e5323dbfc17931bc74b7e0ec51dbf086fd71c' 
  AND token = 'ekbsOdmWX0wjs7ThjnW9EeGifCYDpBnHtXsOR+Ykfoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}