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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e59a69ee9070b0c43eb8eb1b46b424745fca6b7466c1d41eda1e061d3e4c8fe' 
  AND token = 'qj1P3a1MC/MW+P4OpfebBRvuXRAYTwKiF9d10e0Sxrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}