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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7979ba44714c9e6e54f91f9ee0aa88f70961bec3ea09beaf372e38f60cab0c33' 
  AND token = 'HhsK/wo2iLnkOdrodk3KHjiVkI/1ZkGQ5rqhp0zQppQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}