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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd7fd9a182b82f021be22dbca89300547c1c22a2489850ac9e3783a8328c36bb' 
  AND token = 'khc26DIaUs0xv8a+ZC6+2wirgh2Y2+Wg4qbNhxZ2iDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}