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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1860e52a732c30c7fbc102f7f11a4b72554ee12bf06323a97747879280b2b510' 
  AND token = '1+oJ4LAJoiN0hz/eWEXo5watb10DaU5/XP1Xnft7Li8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}